Onychomycosis

The definitive guide to one of the worlds most prevalent dermatologic conditions

Onychomycosis is a fungal nail disease that accounts for 40% of all nail disorders, affecting 1 out of 10 people at some stage in their lives. Compiled by leading dermatologists with expert knowledge of the condition,Onychomycosis: Diagnosis and Effective Managementprovides a clear and clinically focused reference tool for those looking to treat patients expediently and successfully.

This in-depth guide covers all aspects of disease management, from differential diagnosis and lab analysis to topical and systemic treatments. Designed to be a functional and accessible resource, the text also highlights key learning points, with real-life case studies and helpful take-home messages included in each chapter. Coverage of recent innovations and cutting-edge methods ensure the content is relevant to todays dermatologists, while thorough explanations of routine techniques, prognostic factors, and epidemiology make this is an excellent handbook for anyone studying the disease for the first time. The book features:

Onychomycosis is a reliable, easy-to-use companion for trainees and experienced specialists alike, and an invaluable asset to any clinic treating nail conditions.

DIMITRIS RIGOPOULOS, MD, is Professor of Dermatology and Venereology at the Medical School, National and Kapodistrian University of Athens, Athens, Greece.

BONI ELEWSKI, MD, is Professor and Chair of Dermatology at the University of Alabama, Birmingham, AL, USA.

BERTRAND RICHERT, MD, PhD, is Professor of Dermatology and Clinical Professor at Brugmann St Pierre and Queen Fabiola Children's University Hospitals, Université Libre de Bruxelles, Brussels, Belgium.

List of Contributors vii

1 The History of Onychomycosis 1Bárður Sigurgeirsson

2 Epidemiology of Onychomycosis 13Mahmoud A. Ghannoum, Iman Salem, and Luisa Christensen

3 Tinea Pedis and Onychomycosis 21David de Berker

4 Clinical Features: Classification  31Roderick J. Hay

5 Grading Onychomycosis 41Anna Q. Hare and Phoebe Rich

6a Routine and Emerging Techniques in Onychomycosis DiagnosisShari R. Lipner, Richard K. Scher, and Adam I. Rubin 47

6b Histopathology of Onychomycosis 60Josette André

6c Dermoscopy in the Diagnosis of Onychomycosis 66Bianca Maria Piraccini, Aurora Alessandrini, Francesca Bruni, and Michela Starace

7 Differential Diagnosis of Onychomycosis 75Dimitris Rigopoulos and Bertrand Richert

8 Predicting the Outcome of Treatment: Prognostic Factors  83Bárður Sigurgeirsson

9a Topical Therapies for Onychomycosis 103Casey Wang, Theresa Canavan, and Boni Elewski

9b Systemic Treatment of Onychomycosis 118Austin John Maddy and Antonella Tosti

9c(i) Laser Devices in the Treatment of Onychomycosis  123Dimitris Rigopoulos, Christos Prevezas, and Ioanna Triantafyllopoulou

9c(ii) Photodynamic Therapy (PDT) in the Treatment of Onychomycosis  133Elena Sotiriou and Dimitris Ioannides

9c(iii) Onychomycosis and Iontophoresis 141Avner Shemer

9c(iv) Nail Drilling 146Pauline Lecerf

9d Physical Treatment of Onychomycosis 150Bertrand Richert

9e Onychomycosis: Algorithm 160Bertrand Richert

9f Prevention of Relapse and ReInfection: Prophylaxis  162Eckart Haneke

10 Future Treatments for Onychomycosis  173Aditya K. Gupta and Sarah G. Versteeg

11 Onychomycosis in Special Populations 187Nilton Di Chiacchio and Nilton Gioia Di Chiacchio

12 Onychomycosis: The Podiatric Physician Perspective  197Lauren Dabakaroff, Tyrone A. Mayorga, and Bryan C. Markinson

13 Home Remedies for Onychomycosis 207Jane S. Bellet and C. Ralph Daniel, III

Index 213